2. Neurological Disease

Neurological Disease

Neurological Disease

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A range of neurological disorders, including epilepsy and dystonia, may involve dysfunctional intracortical inhibition, and may respond to treatments that modify it. Parkinson’s is a neurodegenerative disease characterized by increased activity of GABA in basal ganglia and the loss of dopamine in nigrostriatum, associated with rigidity, resting tremor, gait with accelerating steps, and fixed inexpressive face. Neurological deficits, along with neuromuscular involvement, are characteristic of mitochondrial disease, and these symptoms can have a dramatic impact on patient quality of life. Neurological features may be manifold, ranging from neural deafness, ataxia, peripheral neuropathy, migraine, seizures, stroke‐like episodes and dementia and depend on the part of the nervous system affected.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W714108
    Metrazoline 221225-04-3 98%
    Metrazoline (o-Methyl-tracizoline) is the ligand for adrenergic receptor (low affinity) and imidazoline I2 receptor.
    Metrazoline
  • HY-W714389
    Cannabifuran 56154-58-6 98%
    Cannabifuran is structurally similar to known phytocannabinoids.
    Cannabifuran
  • HY-W714396
    bk-EABDI hydrochloride 2726084-56-4 98%
    bk-EABDI hydrochloride is a drug derivative characterized by an ethyl group at the alpha position as well as an N-terminal ethyl group.
    bk-EABDI hydrochloride
  • HY-W714406
    Methoxmetamine hydrochloride 1781829-56-8 98%
    Methoxmetamine hydrochloride is structurally categorized as an amphetamine.
    Methoxmetamine hydrochloride
  • HY-W714505
    AH 7563 63886-94-2 98%
    AH 7563 structurally belongs to the opioid compounds and exhibits analgesic activity. In the phenylquinone test and hot plate test, the ED50 of AH 7563 for analgesia in mice were 15.3 mg/kg (orally) and 15.5 mg/kg (subcutaneous injection), respectively.
    AH 7563
  • HY-W714509
    AH 8507 41805-63-4 98%
    AH 8507 structurally belongs to the opioid compounds and is an analog of AH 7563 (HY-W714505). However, AH 8507 does not exhibit significant analgesic effects in mice in both the phenylquinone test and the hot plate test, with ED50 values greater than 100 mg/kg.
    AH 8507
  • HY-W714845
    1-(2-Trifluoromethylphenyl)piperazine hydrochloride 40160-26-7 98%
    1-(2-Trifluoromethylphenyl)piperazine hydrochloride is a piperazine.
    1-(2-Trifluoromethylphenyl)piperazine hydrochloride
  • HY-W715044
    1-(2-Fluorophenyl)piperazine hydrochloride 76835-09-1 98%
    1-(2-Fluorophenyl)piperazine hydrochloride is categorized as a piperazine.
    1-(2-Fluorophenyl)piperazine hydrochloride
  • HY-W715084
    2-CEC hydrochloride 879660-23-8 98%
    2-CEC hydrochloride is structurally categorized as a drug derivative.
    2-CEC hydrochloride
  • HY-W715183
    6α-Oxycodol N-oxide 71539-53-2 98%
    6α-Oxycodol N-oxide is structurally categorized as an opioid. 6α-Oxycodol N-oxide is a metabolite of Oxycodone.
    6α-Oxycodol N-oxide
  • HY-W716866
    10α-Hydroxy-exo-THC 56986-42-6 98%
    10α-hydroxy-exo-THC is a cannabinoid compound, a metabolite of Δ9-THC, and can be found in cannabis. 10α-hydroxy-exo-THC can serve as an analytical reference standard for cannabinoid compounds .
    10α-Hydroxy-exo-THC
  • HY-W718081
    Isopentedrone hydrochloride 1429402-13-0 98%
    Isopentedrone hydrochloride, a drug derivative, a controlled psychoactive stimulant.
    Isopentedrone hydrochloride
  • HY-W718754
    N-Boc norketamine 2177263-88-4 98%
    N-Boc norketamine is an arylcyclohexylamine.
    N-Boc norketamine
  • HY-W719011
    N-Propyl buphedrone hydrochloride 18267-91-9 98%
    N-Propyl buphedrone hydrochloride is a drug derivative.
    N-Propyl buphedrone hydrochloride
  • HY-W720313
    4-Methyl-α-ethylaminobutiophenone hydrochloride 18268-19-4 98%
    4-Methyl-α-ethylaminobutiophenone hydrochloride is a para-methyl analog of buphedrone with an ethyl group replacing methyl at the alpha position.
    4-Methyl-α-ethylaminobutiophenone hydrochloride
  • HY-W720337
    25iP-NBOMe hydrochloride 2725318-60-3 98%
    25iP-NBOMe hydrochloride is classified as a phenethylamine.
    25iP-NBOMe hydrochloride
  • HY-W720532
    N,N-Dimethyl-L-tryptophan hydrochloride 2253893-37-5 98%
    N,N-Dimethyl-L-tryptophan hydrochloride is a tryptamine.
    N,N-Dimethyl-L-tryptophan hydrochloride
  • HY-W721249
    5-Methoxy NMT 2009-03-2
    5-Methoxy NMT is an organic compound of the tryptamine class. 5-Methoxy NMT can be metabolized in the liver by the action of cytochrome p450 enzymes.
    5-Methoxy NMT
  • HY-W721480
    HC-067047 hydrochloride 1481646-76-7 98%
    HC-067047 hydrochloride is a potent and selective TRPV4 antagonist and reversibly inhibits currents through the human, rat, and mouse TRPV4 orthologs with IC50 values of 48 nM, 133 nM, and 17 nM, respectively.
    HC-067047 hydrochloride
  • HY-W721596
    Pentadecanoyl ethanolamide 53832-58-9 98%
    Pentadecanoyl ethanolamide is derivate of endougenous lipid amides, the N-acylethanolamines. Pentadecanoyl ethanolamide exhibits anticonvulsant efficacy in electroshocked mice without significant toxicity.
    Pentadecanoyl ethanolamide
Cat. No. Product Name / Synonyms Application Reactivity